lambda bacteriophage

lambda bacteriophage
(= l phage)
Bacterial DNA virus, first isolated from E. coli. Its structure is similar to that of the T even phages. It shows a lytic cycle and a lysogenic cycle, and studies on the control of these alternative cycles have been very important for our understanding of the regulation of gene transcription. It is used as a cloning vector, accommodating fragments of DNA up to 15 kilobase pairs long. For larger pieces, the cosmid vector was constructed from its ends.

Dictionary of molecular biology. 2004.

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